To show that the impact of self-compassion on occupational stress is mediated by cognitive regulation of affect, a handy group of 328 junior high school teachers was given three questionnaires on occupational stress (Rice, 1992), self-compassion (Neff, 2003), and cognitive regulation of affect (Garnefski, et al. 2001). Data analyses through structural modeling and bootstrapping test revealed that while self-compassion reduces occupational stress, the mediating role of cognitive regulation of affect is also significant. That means in stressful circumstances regulating positive affects, and logical acceptance of negative ones, causes the occupational stress to reduce.